Karyotyping couples experiencing recurrent miscarriage really is worth the cost

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The Investigation and Treatment of Couples with Recurrent Miscarriage

Recurrent miscarriage is a distressing problem that affects 1% of all women. This incidence is greater than that expected by chance alone, since 10–15% of all clinically recognised pregnancies end in a miscarriage and the theoretical risk of three consecutive pregnancy losses is 0.34%. Hence, only a proportion of women presenting with recurrent miscarriage will have a persistent underlying caus...

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Chromosomal abnormalities and embryo development in recurrent miscarriage couples.

BACKGROUND Chromosomal abnormalities are an important cause of spontaneous abortion and recurrent miscarriage (RM). Therefore, we have analysed the incidence of chromosomal abnormalities and embryo development in patients with RM. METHODS Preimplantation genetic diagnosis (PGD) was performed on 71 couples with RM and 28 couples undergoing PGD for sex-linked diseases (control group). Chromosom...

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The Effect of Vitamin E and Selenium on Sperm Chromatin Quality in Couples with Recurrent Miscarriage

Background and Aims: Due to the paucity of studies, association between the morphology and function of sperm and recurrent miscarriage (RM) is not yet completely known. Increased reactive oxygen species and decreased antioxidant levels in men have been shown to be associated with RM. Recently it has been accepted that antioxidant therapy can approve sperm parameters. The goal of this study was ...

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Recurrent miscarriage

Recurrent miscarriages are one or more pregnancy losses before 20-24 weeks of gestation or below a fetal weight of 500 g (Pic. 1). About 1% of women in reproductive age are affected by recurrent miscarriages. The majority of patients are counseled to try to conceive again, and chances are about 60% that the next pregnancy is successful without treatment. However, each additional loss worsens th...

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Recurrent miscarriage

Recurrent miscarriages are one or more pregnancy losses before 20-24 weeks of gestation or below a fetal weight of 500 g (Pic. 1). About 1% of women in reproductive age are affected by recurrent miscarriages. The majority of patients are counseled to try to conceive again, and chances are about 60% that the next pregnancy is successful without treatment. However, each additional loss worsens th...

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ژورنال

عنوان ژورنال: BJOG: An International Journal of Obstetrics & Gynaecology

سال: 2011

ISSN: 1470-0328

DOI: 10.1111/j.1471-0528.2010.02792.x